Khan. A. Wang. G. et al. Chinese Journal of Plastic and Reconstructive Surgery 4 (2022) 187–193
Polynucleotides
Superheroes for your skin
Polynucleotides actively fight the signs of ageing and protect skin from damage.
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Looking for a natural, restorative approach to youthful skin? Polynucleotide treatments are an advanced injectable therapy designed to repair, hydrate, and rejuvenate the skin from within.
At Orchard House in Northallerton, we specialise in polynucleotide treatments that stimulate your skin’s natural repair processes.
What Are Polynucleotides?
Polynucleotides are highly purified DNA fragments that support the skin’s natural repair and regeneration mechanisms. When injected, they stimulate fibroblasts — the cells responsible for producing collagen and elastin — which are essential for maintaining firmness, elasticity, and hydration.
Unlike traditional fillers, which add volume, polynucleotides work from within to improve your skin’s overall quality. Over time, the skin becomes firmer, smoother, and more radiant.
Benefits of Polynucleotide Treatment
Polynucleotides offer multiple skin-enhancing benefits:
1. Hydrated, Radiant Skin
Polynucleotides help attract and retain moisture, leaving your skin fresh, plump, and glowing.
2. Natural Collagen Stimulation
By encouraging collagen and elastin production, polynucleotides improve skin elasticity and firmness, reducing the appearance of fine lines.
3. Smoother Texture
The regenerative effect helps soften rough or uneven skin, including mild acne scarring and sun damage.
4. Repair & Regeneration
Polynucleotides support the skin’s natural repair processes, helping combat environmental damage and early signs of aging.
5. Under-Eye Rejuvenation
They are especially effective for delicate under-eye skin, improving hydration, elasticity, and brightness.
Dr. David injecting polynucleotides under the delicate eye area to improve wrinkling, hydration and dark circles.
Looking for alternative options? Explore all Biostimulator treatments.
Frequently Asked Questions About Polynucleotide Treatment
How Does Polynucleotide Treatment Work?
Polynucleotides work by:
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Stimulating fibroblasts – increasing collagen and elastin production.
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Repairing tissue – improving skin structure and hydration.
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Enhancing elasticity – reducing fine lines and improving firmness.
The treatment is subtle and gradual, with results developing naturally over weeks rather than appearing instantly.
What Skin Concerns Can Polynucleotides Treat?
They improve fine lines, dull or dehydrated skin, reduced elasticity, sun damage, and dark circles under the eyes.
Are Polynucleotide Injections Painful?
Most patients tolerate the treatment well. A topical numbing cream is used to minimise discomfort.
Are Polynucleotides the Same as Dermal Fillers?
No. Dermal fillers add volume, while polynucleotides improve skin quality and regeneration.
Who is Suitable for Treatment?
Polynucleotides are ideal for adults who:
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Want to improve skin quality and hydration
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Are noticing early signs of ageing
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Prefer natural regenerative treatments over fillers
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Have delicate under-eye skin or thin, tired skin
A consultation with our team will help determine if this treatment is right for you.
Can Polynucleotides Be Combined With Other Treatments?
Yes! Polynucleotides work exceptionally well alongside other aesthetic treatments, such as:
How Do I Book A Consultation?
If you want to restore your skin’s natural glow and firmness, polynucleotide treatment may be the perfect choice for you. This will be discussed with you during your consultation.